ePrints@IIScePrints@IISc Home | About | Browse | Latest Additions | Advanced Search | Contact | Help

Browse by Author

Up a level
Export as [feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
Group by: Item Type | No Grouping
Number of items: 38.

Book Chapter

Ray, U and Raghavan, SC (2022) Nonhomologous DNA End Joining in Mammalian Cells. [Book Chapter]

Journal Article

Gopalakrishnan, V and Roy, U and Srivastava, S and Kariya, KM and Sharma, S and Javedakar, SM and Choudhary, B and Raghavan, SC (2024) Delineating the mechanism of fragility at BCL6 breakpoint region associated with translocations in diffuse large B cell lymphoma. In: Cellular and Molecular Life Sciences, 81 (1).

Joy, R and Siddiqua, H and Sharma, S and Raveendran, M and John, F and Hassan, PA and Gawali, SL and Raghavan, SC and George, J (2023) Block Copolymer Encapsulation of Disarib, an Inhibitor of BCL2 for Improved Chemotherapeutic Potential. In: ACS Omega .

Kumari, N and Antil, H and Kumari, S and Raghavan, SC (2023) Deficiency of ligase IV leads to reduced NHEJ, accumulation of DNA damage, and can sensitize cells to cancer therapeutics. In: Genomics, 115 (6).

Prabhu, DJ and Ray, U and Rajeev, A and Joy, R and George, AT and George, J and Raghavan, SC and John, F (2023) Design and Synthesis of Ketenimine Sulfonamide Conjugates through Multicomponent Reactions; A Combined Cytotoxic Analysis and Computational Exploration. In: ACS Omega, 8 (41). pp. 38619-38631.

Kumari, N and Das, K and Sharma, S and Dahal, S and Desai, SS and Roy, U and Sharma, A and Manjunath, M and Gopalakrishnan, V and Retheesh, ST and Javadekar, SM and Choudhary, B and Raghavan, SC (2023) Evaluation of potential role of R-loop and G-quadruplex DNA in the fragility of c-MYC during chromosomal translocation associated with Burkitt's lymphoma. In: Journal of Biological Chemistry, 299 (12).

Ghosh, D and Nilavar, NM and Raghavan, SC (2022) A novel KU70-mutant human leukemic cell line generated using CRISPR-Cas9 shows increased sensitivity to DSB inducing agents and reduced NHEJ activity. In: Biochimica et Biophysica Acta - General Subjects, 1866 (12).

Sharma, A and Kaninathan, A and Dahal, S and Kumari, S and Choudhary, B and Raghavan, SC (2022) Exposure to endosulfan can cause long term effects on general biology, including the reproductive system of mice. In: Frontiers in Genetics, 13 .

Ray, U and Gopinatha, VK and Sharma, S and Goyary, L and Choudhary, B and Mantelingu, K and Rangappa, KS and Raghavan, SC (2022) Identification and characterization of mercaptopyrimidine-based small molecules as inhibitors of nonhomologous DNA end joining. In: FEBS Journal .

Ghosh, D and Kumari, S and Raghavan, SC (2022) Depletion of RNASEH2 Activity Leads to Accumulation of DNA Double-strand Breaks and Reduced Cellular Survivability in T Cell Leukemia. In: Journal of Molecular Biology, 434 (12).

Desai, SS and Whadgar, S and Raghavan, SC and Choudhary, B (2022) MiRAGDB: A Knowledgebase of RAG Regulators. In: Frontiers in Immunology, 13 .

Sharma, S and Varsha, KK and Ray, U and Siddiqua, H and Jose, AE and Muninarasimaiah, S and Raghavan, SC and Choudhary, B (2021) Acute toxicity analysis of an inhibitor of BCL2, Disarib, in rats. In: Scientific Reports, 11 (1).

Ray, U and Raghavan, SC (2021) Understanding the DNA double-strand break repair and its therapeutic implications. In: DNA Repair, 106 .

Ghosh, D and Raghavan, SC (2021) Nonhomologous end joining: new accessory factors fine tune the machinery. In: Trends in Genetics .

Kumari, N and Raghavan, SC (2021) G-quadruplex DNA structures and their relevance in radioprotection. In: Biochimica et Biophysica Acta - General Subjects, 1865 (5).

Dahal, S and Raghavan, SC (2021) Mitochondrial genome stability in human: understanding the role of DNA repair pathways. In: Biochemical Journal, 478 (6). pp. 1179-1197.

Ghosh, D and Raghavan, SC (2021) 20 years of DNA Polymerase μ, the polymerase that still surprises. In: FEBS Journal .

Dahal, S and Siddiqua, H and Katapadi, VK and Iyer, D and Raghavan, SC (2021) Characterization of G4 DNA formation in mitochondrial DNA and their potential role in mitochondrial genome instability. In: FEBS Journal .

Roy, U and Raghavan, SC (2021) Deleterious point mutations in T-cell acute lymphoblastic leukemia: Mechanistic insights into leukemogenesis. In: International Journal of Cancer .

Ray, U and Sharma, S and Kapoor, I and Kumari, S and Gopalakrishnan, V and Vartak, SV and Kumari, N and Varshney, U and Raghavan, SC (2021) G4 DNA present at human telomeric DNA contributes toward reduced sensitivity to γ-radiation induced oxidative damage, but not bulky adduct formation. In: International Journal of Radiation Biology .

Nilavar, NM and Raghavan, SC (2021) HIV integrase inhibitors that inhibit strand transfer interact with RAG1 and hamper its activities. In: International Immunopharmacology, 95 .

Sharath Kumar, KS and Ananda, H and Rangappa, S and Raghavan, SC and Rangappa, KS (2021) Regioselective competitive synthesis of 3,5-bis(het) aryl pyrrole-2-carboxylates/carbonitriles vs. β-enaminones from β-thioxoketones. In: Tetrahedron Letters .

Manjunath, M and Choudhary, B and Raghavan, SC (2021) SCR7, a potent cancer therapeutic agent and a biochemical inhibitor of nonhomologous DNA end-joining. In: Cancer Reports .

Ray, U and Vartak, SV and Raghavan, SC (2020) NHEJ inhibitor SCR7 and its different forms: Promising CRISPR tools for genome engineering. In: Gene, 763 .

Sharma, S and Varsha, KK and Kumari, S and Gopalakrishnan, V and Jose, AE and Choudhary, B and Mantelingu, K and Raghavan, SC (2020) Acute toxicity analysis of Disarib, an inhibitor of BCL2. In: Scientific Reports, 10 (1).

Nilavar, NM and Paranjape, AM and Raghavan, SC (2020) Biochemical activity of RAGs is impeded by Dolutegravir, an HIV integrase inhibitor. In: Cell Death Discovery, 6 (1).

Ray, U and Raghavan, SC (2020) Inhibitors of DNA double-strand break repair at the crossroads of cancer therapy and genome editing. In: Biochemical Pharmacology, 182 .

Ray, U and Raghavan, SC (2020) Modulation of DNA double-strand break repair as a strategy to improve precise genome editing. In: Oncogene .

Javadekar, SM and Nilavar, NM and Paranjape, A and Das, K and Raghavan, SC (2020) Characterization of G-quadruplex antibody reveals differential specificity for G4 DNA forms. In: DNA Research, 27 (5).

Gopinatha, Vindya K and Ray, U and Mantelingu, K and Raghavan, SC and Rangappa, KS (2020) Synthesis and Biological Evaluation of Theophylline Methyl 1,3,4-Oxadiazole as Anticancer Agents. In: Russian Journal of Bioorganic Chemistry, 46 (5). pp. 837-844.

Nilavar, NM and Nishana, M and Paranjape, AM and Mahadeva, R and Kumari, R and Choudhary, B and Raghavan, SC (2020) Znc2 module of RAG1 contributes towards structure-specific nuclease activity of RAGs. In: Biochemical Journal, 477 (18). pp. 3567-3582.

Ray, U and Raul, SK and Gopinatha, VK and Ghosh, D and Rangappa, KS and Mantelingu, K and Raghavan, SC (2020) Identification and characterization of novel SCR7-based small-molecule inhibitor of DNA end-joining, SCR130 and its relevance in cancer therapeutics. In: Molecular Carcinogenesis, 59 (6). pp. 618-628.

Ray, U and John, F and Pooppadi, S and George, J and Sharma, S and Raghavan, SC (2020) Novel synthetic aromatic thiourea derivatives and investigations on their cytotoxic potential efficacy. In: Journal of Heterocyclic Chemistry .

Mishra, S and Tamta, AK and Sarikhani, M and Desingu, PA and Kizkekra, SM and Pandit, AS and Kumar, S and Khan, D and Raghavan, SC and Sundaresan, NR (2018) Subcutaneous Ehrlich Ascites Carcinoma mice model for studying cancer-induced cardiomyopathy. In: Scientific Reports, 8 (1).

Sharma, S and Javadekar, SM and Pandey, M and Srivastava, M and Kumari, R and Raghavan, SC (2015) Homology and enzymatic requirements of microhomology-dependent alternative end joining. In: CELL DEATH & DISEASE, 6 .

Prasanna, DS and Kavitha, CV and Raghava, B and Vinaya, K and Ranganatha, SR and Raghavan, SC and Rangappa, KS (2010) Synthesis and identification of a new class of (S)-2,6-diamino-4,5,6,7-tetrahydrobenzo[d]thiazole derivatives as potent antileukemic agents. In: Investigational New Drugs, 28 (4). pp. 1573-0646.

Raghavan, SC and Lieber, MR (2007) DNA structure and human diseases. In: Frontiers in Bioscience, 12 . pp. 4402-4408.

Editorials/Short Communications

Sebastian, R and Raghavan, SC (2015) Endosulfan induces male infertility. In: CELL DEATH & DISEASE, 6 .

This list was generated on Fri Apr 26 03:45:59 2024 IST.