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DNA structure and human diseases

Raghavan, SC and Lieber, MR (2007) DNA structure and human diseases. In: Frontiers in Bioscience, 12 . pp. 4402-4408.

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Official URL: http://www.bioscience.org/2007/v12/af/2397/fulltex...


Recently, multiple lines of evidences have shown that non-B DNA structures within the human genes may lead to chromosomal translocations, deletions and amplifications in cancer and other human diseases. In this review, we summarize the current literature on non-B DNA structures, and discuss their role in genomic instability and diseases.

Item Type: Journal Article
Publication: Frontiers in Bioscience
Publisher: Frontiers in Bioscience Inc
Additional Information: Copyright of this article belongs to Frontiers in Bioscience Inc.
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 16 Jul 2007
Last Modified: 30 Jan 2012 06:09
URI: http://eprints.iisc.ac.in/id/eprint/11581

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