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Singh, J and Singh, S and Emam, EAF and Varshney, U (2024) Role of Rmd9p in 3�-end processing of mitochondrial 15S rRNA in Saccharomyces cerevisiae. In: Mitochondrion, 76 .
Lahry, K and Datta, M and Varshney, U (2024) Genetic analysis of translation initiation in bacteria: An initiator tRNA-centric view. In: Molecular Microbiology .
Emam, EAF and Roy, K and Varshney, U (2024) An exchange of single amino acid between the phosphohydrolase modules of Escherichia coli MutT and Mycobacterium smegmatis MutT1 switches their cleavage specificities. In: DNA Repair, 139 .
Varshney, U (2023) Co-evolution of the translation apparatus and eukaryotes. In: Journal of Biosciences, 48 (4).
Kesharwani, S and Raj, P and Paul, A and Roy, K and Bhanot, A and Mehta, A and Gopal, A and Varshney, U and Gopal, B and Sundriyal, S (2023) Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment. In: European Journal of Medicinal Chemistry, 258 .
Singh, S and Lahry, K and Mandava, CS and Singh, J and Shah, RA and Sanyal, S and Varshney, U (2023) Lamotrigine compromises the fidelity of initiator tRNA recruitment to the ribosomal P-site by IF2 and the RbfA release from 30S ribosomes in Escherichia coli. In: RNA Biology, 20 (1). pp. 681-692.
Aroli, S and Woo, E-J and Gopal, B and Varshney, U (2023) Mutational and structural analyses of UdgX: Insights into the active site pocket architecture and its evolution. In: Nucleic Acids Research, 51 (13). pp. 6554-6565.
Sah, S and Varshney, U (2023) Methionyl-tRNA formyltransferase utilizes 10-formyldihydrofolate as an alternative substrate and impacts antifolate drug action. In: Microbiology (United Kingdom), 169 (2).
Naz, S and Paritosh, K and Sanyal, P and Khan, S and Singh, Y and Varshney, U and Nandicoori, VK (2023) GWAS and functional studies suggest a role for altered DNA repair in the evolution of drug resistance in Mycobacterium tuberculosis. In: eLife, 12 .
Raj, P and Selvam, K and Roy, K and Mani Tripathi, S and Kesharwani, S and Gopal, B and Varshney, U and Sundriyal, S (2022) Identification of a new and diverse set of Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) inhibitors using structure-based virtual screening: Experimental validation and molecular dynamics studies. In: Bioorganic and Medicinal Chemistry Letters, 76 .
Kapoor, I and Shaw, A and Naha, A and Emam, E A F and Varshney, U (2022) Role of the nucleotide excision repair pathway proteins (UvrB and UvrD2) in recycling UdgB, a base excision repair enzyme in Mycobacterium smegmatis. In: DNA Repair, 113 .
Raja, S and Paul, A and Raghavan, S and Narayanan, S and Shee, S and Singh, A and Varshney, U and Gopal, B and Vijayan, M (2022) Structural variability of Mycobacterium tuberculosis SSB and susceptibility to inhibition. In: Current Science, 122 (3). pp. 281-289.
Datta, M and Singh, J and Modak, MJ and Pillai, M and Varshney, U (2022) Systematic evolution of initiation factor 3 and the ribosomal protein uS12 optimizes Escherichia coli growth with an unconventional initiator tRNA. In: Molecular Microbiology, 117 (2). pp. 462-479.
Singh, J and Mishra, RK and Ayyub, SA and Hussain, T and Varshney, U (2022) The initiation factor 3 (IF3) residues interacting with initiator tRNA elbow modulate the fidelity of translation initiation and growth fitness in Escherichia coli. In: Nucleic Acids Research, 50 (20). pp. 11712-11726.
Mehta, A and Raj, P and Sundriyal, S and Gopal, B and Varshney, U (2021) Use of a molecular beacon based fluorescent method for assaying uracil DNA glycosylase (Ung) activity and inhibitor screening. In: Biochemistry and Biophysics Reports, 26 .
Shetty, S and Varshney, U (2021) Regulation of translation by one-carbon metabolism in bacteria and eukaryotic organelles. In: Journal of Biological Chemistry, 296 .
Ray, U and Sharma, S and Kapoor, I and Kumari, S and Gopalakrishnan, V and Vartak, SV and Kumari, N and Varshney, U and Raghavan, SC (2021) G4 DNA present at human telomeric DNA contributes toward reduced sensitivity to γ-radiation induced oxidative damage, but not bulky adduct formation. In: International Journal of Radiation Biology .
Datta, M and Pillai, M and Modak, MJ and Liiv, A and Khaja, FT and Hussain, T and Remme, J and Varshney, U (2020) A mutation in the ribosomal protein uS12 reveals novel functions of its universally conserved PNSA loop. In: Molecular Microbiology . (In Press)
Raj, P and Karthik, S and Arif, SM and Varshney, U and Vijayan, M (2020) Plasticity, ligand conformation and enzyme action of Mycobacterium smegmatis MutT1. In: Acta Crystallographica Section D: Structural Biology, 76 . pp. 982-992.
Kapoor, I and Varshney, U (2020) Diverse roles of nucleoside diphosphate kinase in genome stability and growth fitness. In: Current Genetics, 66 (4). pp. 671-682.
Tharp, JM and Krahn, N and Varshney, U and Soll, D (2020) Hijacking Translation Initiation for Synthetic Biology. In: ChemBioChem, 21 (10). pp. 1387-1396.
Kurthkoti, K and Kumar, P and Sang, PB and Varshney, U (2020) Base excision repair pathways of bacteria: New promise for an old problem. In: Future Medicinal Chemistry, 12 (4). pp. 339-355.
Lahry, K and Gopal, A and Sah, S and Shah, RA and Varshney, U (2020) Metabolic Flux of N10-Formyltetrahydrofolate Plays a Critical Role in the Fidelity of Translation Initiation in Escherichia coli. In: Journal of Molecular Biology .
Ravi, V and Jain, A and Khan, D and Ahamed, F and Mishra, S and Giri, M and Inbaraj, M and Krishna, S and Sarikhani, M and Maity, S and Kumar, S and Shah, RA and Dave, P and Pandit, AS and Rajendran, R and Desingu, PA and Varshney, U and Das, S and Kolthur-Seetharam, U and Rajakumari, S and Singh, M and Sundaresan, NR (2019) SIRT6 transcriptionally regulates global protein synthesis through transcription factor Sp1 independent of its deacetylase activity. In: Nucleic Acids Research, 47 (17). pp. 9115-9131.
Shah, RA and Varada, R and Sah, S and Shetty, S and Lahry, K and Singh, S and Varshney, U (2019) Rapid formylation of the cellular initiator tRNA population makes a crucial contribution to its exclusive participation at the step of initiation. In: Nucleic acids research, 47 (4). pp. 1908-1919.
Govindan, A and Ayyub, SA and Varshney, U (2018) Sustenance of Escherichia coli on a single tRNAMet. In: Nucleic acids research, 46 (21). pp. 11566-11574.
Ayyub, SA and Aswathy, SL and Dobriyal, D and Aluri, S and Spremulli, LL and Varshney, U (2018) Fidelity of translation in the presence of mammalian mitochondrial initiation factor 3. In: Mitochondrion, 39 . pp. 1-8.
Arif, SM and Patil, AG and Varshney, U and Vijayan, M (2017) Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association. In: ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 73 (4). pp. 349-364.
Arif, SM and Varshney, U and Vijayan, M (2017) Hydrolysis of diadenosine polyphosphates. Exploration of an additional role of Mycobacterium smegmatis MutT1. In: JOURNAL OF STRUCTURAL BIOLOGY, 199 (3). pp. 165-176.
Arif, SM and Geethanandan, K and Mishra, P and Surolia, A and Varshney, U and Vijayan, M (2015) Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications. In: ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 71 (7). pp. 1514-1527.
Selvaraj, M and Govindan, A and Seshadri, A and Dubey, B and Varshney, U and Vijayan, M (2013) Molecular flexibility of Mycobacterium tuberculosis ribosome recycling factor and its functional consequences: An exploration involving mutants. In: JOURNAL OF BIOSCIENCES, 38 (5). pp. 845-855.
Arif, SM and Patil, AG and Varshney, U and Vijayan, M (2012) Crystallization and preliminary X-ray studies of MutT1 (MSMEG_2390) from Mycobacterium smegmatis. In: ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS, 68 (Part 1). pp. 1214-1216.
Kapoor, S and Samhita, L and Varshney, U (2011) Functional Significance of an Evolutionarily Conserved Alanine (GCA) Resume Codon in tmRNA in Escherichia coli. In: Journal of Bacteriology, 193 (14). pp. 3569-3576. ISSN 0021-9193
Singh, A and Varshney, U and Vijayan, M (2017) Characterization of a second Single Stranded DNA Binding protein from Mycobacterium smegmatis. In: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 46 (1). S147.
