Whaley, Kevin J and Sampatha, DS and Balaram, P (1984) Optically active gossypol as a circular dichroism probe of interactions with serum albumins. In: Biochimica et Biophysica Acta, 801 (1). pp. 127-130.
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Abstract
The (+)-enantiomer of the polyphenolic binaphthyl gossypol, has been shown to be a useful CD probe of interactions with human and bovine serum albumin. (+)-Gossypol binds to albumin with same affinity as recemic (±)-gossypol, as shown by fluorescence quenching, and also displaces bilirubin from its albumin binding site. The CD characteristics of bound gossypol are different in the case of the two proteins.
| Item Type: | Journal Article |
|---|---|
| Publication: | Biochimica et Biophysica Acta |
| Publisher: | Elsevier Science |
| Additional Information: | Copyright for this article belongs to Elsevier Science. |
| Department/Centre: | Division of Biological Sciences > Molecular Biophysics Unit |
| Date Deposited: | 03 Feb 2010 12:15 |
| Last Modified: | 19 Sep 2010 05:34 |
| URI: | http://eprints.iisc.ac.in/id/eprint/20709 |
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