X-Ray analysis of a complex of Escherichia Coli uracil DNA glycosylase(EcUDG) with a proteinaceous inhibitor. The structure elucidation of a prokaryotic UDG.

Ravishankar, R and Sagar, Bidya M and Roy, S and Purnapatre, K and Handa, P and Varshney, U and Vijayan, M (1998) X-Ray analysis of a complex of Escherichia Coli uracil DNA glycosylase(EcUDG) with a proteinaceous inhibitor. The structure elucidation of a prokaryotic UDG. In: Nucleic Acids Research, 26 (21). pp. 4880-4887.

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Abstract

Uracil-DNA glycosynase(UDG), a highly conserved repair enzyme involved in uracil excision repair, was diacovered in Escherichia Coli. The Bacillus subtillis bacteriophage, PBS-1 and PBS-2 which contain dump residues in their DNA, express a UDG inhibitor protein, Ugi which binds to UDG very tightly to form a physiologically irreversible complex.

Item Type:	Journal Article
Publication:	Nucleic Acids Research
Publisher:	Oxford University Press
Additional Information:	The copyright belongs to Oxford University Press
Keywords:	x ray analysis;escherichia coli;dna glycosylase;uracil
Department/Centre:	Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited:	25 Aug 2004
Last Modified:	19 Sep 2010 04:14
URI:	http://eprints.iisc.ac.in/id/eprint/1330

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