Banerjee, A and Basu, B and Saha, S and Chowdhury, AR (2023) Design and development of a patient-specific temporomandibular joint implant: Probing the influence of bone condition on biomechanical response. In: Journal of Biomedical Materials Research - Part B Applied Biomaterials, 111 (12). 2089 -2097.
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Abstract
Total temporomandibular joint (TMJ) replacement is widely recognized as an effective treatment for TMJ disorders. The long-term stability of TMJ implants depends on two important factors which are design concepts for fixation to anatomical locations in the mandible and bone conditions. Other factors include stress distribution, microstrain in the peri-implant, bone attributes like bone conditions leading to the clinical complications and failures. This study addresses these limitations by examining the influence of patient-specific design concepts and bone conditions on TMJ implant performance. Clinical evidences support the importance of implant design on healing ability. Previous studies have focused on achieving precise implant fit based on geometric considerations, however those published studies did not explore the impact of such. Against this perspective, the present study reports the extensive finite element analysis (FEA) results, while analyzing the impact of a newly designed patient-specific TMJ implant to address clinical complications associated with various bone conditions, particularly osteoporotic bone. In validating the FEA results, the performance of additively manufactured patient-specific TMJ implants was compared with designs resembling two commonly used clinically approved implant designs. By addressing the limitations of previous research and emphasizing the importance of bone conditions, the study provides valuable guidelines for the development of next-generation TMJ implants. These findings contribute to enhanced clinical outcomes and long-term success in the treatment of TMJ disorders. © 2023 Wiley Periodicals LLC.
| Item Type: | Journal Article |
|---|---|
| Publication: | Journal of Biomedical Materials Research - Part B Applied Biomaterials |
| Publisher: | John Wiley and Sons Inc |
| Additional Information: | The copyright for this article belongs to the Authors. |
| Keywords: | Bone, Clinical complications; Condition; Design concept; Implant design; Joint implants; Maxillofacial; Patient specific; Temporomandibular joint; Temporomandibular joint disorders; Temporomandibular joint implant, Joints (anatomy) |
| Department/Centre: | Division of Chemical Sciences > Materials Research Centre |
| Date Deposited: | 05 Nov 2023 06:05 |
| Last Modified: | 05 Nov 2023 06:05 |
| URI: | https://eprints.iisc.ac.in/id/eprint/83077 |
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