Reddy, PO and Reddy, AA and Prasad, KR (2020) Stereoselective Synthesis of β-Amino Ynones by the Addition of Alkynones to Nonracemic Sulfinimines: Formal Total Synthesis of l-Xylo and l-Arabino Phytosphingosines. In: Journal of Organic Chemistry, 85 (4). pp. 2743-2751.
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Official URL: https://doi.org/10.1021/acs.joc.9b02938
Abstract
The addition of silyl enol ethers obtained from ynones to sulfinimines furnished the corresponding β-sulfinamido ynones in a very good yield and diastereoselectivity. The formed ynones serve as precursors amenable for the synthesis of bioactive compounds. This has been illustrated in the synthesis of l-xylo and l-Arabino phytosphingosines
Item Type: | Journal Article |
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Publication: | Journal of Organic Chemistry |
Publisher: | American Chemical Society |
Additional Information: | The copyright for this article belongs to the American Chemical Society. |
Keywords: | Stereochemistry, Alkynones; Bioactive compounds; Diastereo-selectivity; Phytosphingosines; Silyl enol ethers; Stereoselective synthesis; Sulfinimines; Total synthesis, Stereoselectivity, article; diastereoisomer |
Department/Centre: | Division of Chemical Sciences > Organic Chemistry |
Date Deposited: | 02 Feb 2023 06:48 |
Last Modified: | 02 Feb 2023 06:48 |
URI: | https://eprints.iisc.ac.in/id/eprint/79724 |
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