Fascinating fungal endophytes associated with medicinal plants: Recent advances and beneficial applications

Rao, HCY and Kamalraj, S and Jayabaskaran, C (2019) Fascinating fungal endophytes associated with medicinal plants: Recent advances and beneficial applications. [Book Chapter]

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Abstract

Fungal endophytes are a group of microbes that reside in the inside plant tissues parts without showing any evident harmful to the host and feature continuous metabolic interactions with their host. Endophytes can firmly establish plant-endophyte as well as microbial interactions which play a significant role in the biosynthesis of secondary metabolites. Some plants lack immunity against various invading pathogens which might affect its function and growth, but endophytes reside in the host tissue can increase the immunity power to the host plant to fight against various invading pathogens. They are highly considered as underexplored drug reservoir having the capability to biosynthesize new bioactive compounds. Scads of the secondary metabolites belong to different classes of molecules like alkaloids, terpenoids, chromones, isocoumarin derivatives, peptides, xanthones, lactones, cytochalasins, quinones, phenolic acids, enniatines, and steroids. Due to their high chemical diversity of biological compounds, fungal endophytes have been explored for agricultural, industrial, and medicinal uses. Further, we explore the recent innovations to enhance the implication of fungal endophytes and their natural products by the agricultural and pharmaceutical industries. In this backdrop, our main focus lies on exploring the applications of fungal endophytes and their bioactive compounds in the view of developing novel potential drugs. © 2020 Elsevier Inc. All rights reserved.

Item Type:	Book Chapter
Publication:	Microbial Endophytes: Prospects for Sustainable Agriculture
Publisher:	Elsevier
Additional Information:	The copyright for this article belongs to Elsevier.
Keywords:	Bioactive compounds; Endophytic fungi; Medicinal plants; Novel drugs; Secondary metabolites
Department/Centre:	Division of Biological Sciences > Biochemistry
Date Deposited:	06 Jan 2023 05:15
Last Modified:	06 Jan 2023 05:15
URI:	https://eprints.iisc.ac.in/id/eprint/78800

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