Cobalt(III)-Catalyzed 4 + 2 Annulation of N-Chlorobenzamides with Maleimides

Muniraj, N and Prabhu, KR (2019) Cobalt(III)-Catalyzed 4 + 2 Annulation of N-Chlorobenzamides with Maleimides. In: Organic Letters, 21 (4). pp. 1068-1072.

PDF Org_Let_21-4_1068-1072_2019.pdf - Published Version Restricted to Registered users only Download (12MB) | Request a copy

Abstract

A Co(III)-catalyzed novel 4 + 2 annulation of N-chlorobenzamides with maleimides has been reported. Mostly, maleimides are known to furnish the Michael-type or 1,1-type cyclized products while treating with amides. In this reaction, maleimides furnished 4 + 2 annulated products in good yields at room temperature while being treated with the internal oxidizing N-chlorobenzamide as a directing group. The developed methodology is compatible with a variety of functional groups. The 4 + 2 annulated products obtained are featured in some biologically active molecules. Copyright © 2019 American Chemical Society.

Item Type:	Journal Article
Publication:	Organic Letters
Publisher:	American Chemical Society
Additional Information:	The copyright for this article belongs to American Chemical Society.
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	13 Dec 2022 05:05
Last Modified:	13 Dec 2022 05:05
URI:	https://eprints.iisc.ac.in/id/eprint/78330

Actions (login required)

View Item