Anand, A and Khanapurmath, N and Kulkarni, MV and Guru Row, TN (2022) Biheterocyclic Coumarins: A Simple yet Versatile Resource for Futuristic Design and Applications in Bio-molecular and Material Chemistry. In: Current Organic Chemistry, 26 (5). pp. 444-506.
Full text not available from this repository.Abstract
Coumarin derivatives occur widely in nature and are a part of both traditional and modern advancements in synthesis and application. To date, thousands of coumarin derivatives have been synthesized in lab or isolated from plant and marine life. These are essentially 2-pyrone core fused with a benzene ring and belong to the family of aromatic oxygen heterocy-cles. Coumarin in conjugation with various other heterocyclic systems has provided a robust framework for tuning the properties associated with the parent structure. The frequency of reports has increased for these biheterocyclic systems from the mid twentieth century. Biheter-ocyclic coumarins have also attracted the attention of many organic and pharmaceutical chemists as these systems serve as useful synthetic intermediates in the synthesis of analogs of ex-isting drugs. Their application in the design of effective organocatalysts and chemosensors has further extended their versatility. Coumarin biheterocyclic core is utilized in the rational design and tuning of complex molecular entities in molecular recognition, analytical and material chemistry. This review highlights the advancements in the synthesis and applications of coumarin-linked nitrogen, oxygen, and sulfur heterocycles. It also provides an account of five-, six-, and seven-membered heterocyclic rings linked to coumarin core. Critical physi-cochemical properties coupled with their application will make this review useful for synthetic chemists and drug discovery labs. A comprehensive spectrum of literature in this review will facilitate further development of biheter-ocycles along with their promising applications in the future. © 2022 Bentham Science Publishers.
| Item Type: | Journal Article |
|---|---|
| Publication: | Current Organic Chemistry |
| Publisher: | Bentham Science Publishers |
| Additional Information: | The copyright for this article belongs to the Bentham Science Publishers. |
| Department/Centre: | Division of Chemical Sciences > Solid State & Structural Chemistry Unit |
| Date Deposited: | 21 Sep 2022 09:46 |
| Last Modified: | 21 Sep 2022 09:46 |
| URI: | https://eprints.iisc.ac.in/id/eprint/76946 |
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