Naz, A and Chowdhury, A and Pareek, S and Kumar, P and Poddar, NK (2024) A critical review on the active anti-viral metabolites of bioprospecting traditionally used plant species from semi-arid regions of the subcontinent. In: Journal of Complementary and Integrative Medicine .
Full text not available from this repository. (Request a copy)Abstract
Plants are crucial medicinal resources, with 80 of people relying on them for primary healthcare. The search for natural antiviral compounds is increasing, especially in semi-arid ecosystems where abiotic stress promotes the production of beneficial secondary metabolites. This review highlights semi-arid plants with the potential as functional foods to combat viral diseases and other illnesses. Literature was searched in databases like ScienceDirect to gather information on novel compounds from stress-tolerant semiarid plant species. These compounds have potential uses in treating viral infections and other health issues such as diabetes and high blood pressure. The review screened 61 semi-arid plants known for their antiviral metabolites. Eight plants were identified with novel antiviral compounds. Key metabolites include agathisflavone, pectic arabinogalactan, azadirachtin, aloin, aloe-emodin, aloesaponarin I, allicin, terpenoids, chlorogenic acids, curcumin, chromones, β-sitosterol, lupeol, oleuropein, carissol, β-amyrin, and �-9-tetrahydrocannabinol. Stress-tolerant semi-arid plants are significant sources of metabolites for treating infectious diseases and boosting immune systems. Further research on these metabolites in animal models is needed to verify their efficacy for treating human diseases during endemic and pandemic outbreaks, such as COVID-19. © 2024 Walter de Gruyter GmbH. All rights reserved.
| Item Type: | Journal Article |
|---|---|
| Publication: | Journal of Complementary and Integrative Medicine |
| Publisher: | Walter de Gruyter GmbH |
| Additional Information: | The copyright for this article belongs to the publishers. |
| Keywords: | allicin; aloe emodin; aloin; antivirus agent; arabinogalactan; azadirachtin; beta amyrin; chlorogenic acid; chromone derivative; curcumin; dronabinol; lupeol; oleuropein; sitosterol; terpenoid, abiotic stress; animal model; antiviral activity; biopanning; bioprospecting; coronavirus disease 2019; drug analysis; functional food; human; hypertension; metabolite; nonhuman; pharmacognosy; pharmacology; review; traditional medicine |
| Department/Centre: | Division of Mechanical Sciences > Materials Engineering (formerly Metallurgy) |
| Date Deposited: | 19 Nov 2024 19:26 |
| Last Modified: | 19 Nov 2024 19:26 |
| URI: | http://eprints.iisc.ac.in/id/eprint/86763 |
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