4D printing for biomedical applications

Mandal, A and Chatterjee, K (2024) 4D printing for biomedical applications. In: Journal of Materials Chemistry B .

PDF Jou_mat_che_2024.pdf - Published Version Restricted to Registered users only Download (3MB) | Request a copy

Abstract

While three-dimensional (3D) printing excels at fabricating static constructs, it fails to emulate the dynamic behavior of native tissues or the temporal programmability desired for medical devices. Four-dimensional (4D) printing is an advanced additive manufacturing technology capable of fabricating constructs that can undergo pre-programmed changes in shape, property, or functionality when exposed to specific stimuli. In this Perspective, we summarize the advances in materials chemistry, 3D printing strategies, and post-printing methodologies that collectively facilitate the realization of temporal dynamics within 4D-printed soft materials (hydrogels, shape-memory polymers, liquid crystalline elastomers), ceramics, and metals. We also discuss and present insights about the diverse biomedical applications of 4D printing, including tissue engineering and regenerative medicine, drug delivery, in vitro models, and medical devices. Finally, we discuss the current challenges and emphasize the importance of an application-driven design approach to enable the clinical translation and widespread adoption of 4D printing. © 2024 The Royal Society of Chemistry

Item Type:	Journal Article
Publication:	Journal of Materials Chemistry B
Publisher:	Royal Society of Chemistry
Additional Information:	The copyright for this article belongs to Royal Society of Chemistry.
Keywords:	Medical applications; Tissue; Tissue engineering, Additive manufacturing technology; Biomedical applications; Dynamic behaviors; Excel; Exposed to; Material chemistry; Medical Devices; Programmability; Shape property; Three-dimensional (3D) printing, Drug delivery
Department/Centre:	Division of Mechanical Sciences > Materials Engineering (formerly Metallurgy)
Date Deposited:	14 May 2024 10:41
Last Modified:	14 May 2024 10:41
URI:	https://eprints.iisc.ac.in/id/eprint/84434

Actions (login required)

View Item