Biosynthesis of zinc oxide nanoparticles mediated by Strobilanthes hamiltoniana: Characterizations, and its biological applications

Gangwar, J and Balasubramanian, B and Pratap Singh, A and Meyyazhagan, A and Pappuswamy, M and Alanazi, AM and Rengasamy, KRR and Kadanthottu Sebastian, J (2023) Biosynthesis of zinc oxide nanoparticles mediated by Strobilanthes hamiltoniana: Characterizations, and its biological applications. In: Kuwait Journal of Science .

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Abstract

Nanoparticles of Zinc oxide (ZnONPs), has a variety of applications such as antibacterial property, water treatment for pollutant removal, and as catalysts for organic reactions etc. and have been synthesized utilizing a variety of approaches, including green synthesis, chemical precipitation, sol�gel, hydrothermal synthesis, and microwave-assisted synthesis. In the present work, easy and economically viable ZnONPs were synthesized utilizing Strobilanthes hamiltoniana (SH) leaf extracts. Phytochemicals form S. hamiltoniana act as agents for reducing and capping the metal oxide ions. A range of analytical and microscopic techniques have been used to investigate the physical and chemical properties of ZnONPs. At 360 �nm, green synthesized SH-ZnONPs showed robust UV�Vis absorption. The nanosize, shape, and crystalline structure of SH-ZnO NPs were characterized using XRD and electron microscopy techniques. Using SH-ZnO NPs, the photocatalytic activity of textile dyes such as Reactive blue 220 (RB-220), Reactive blue 222A (RB-222A), Reactive yellow 145 (RY-145) and Reactive yellow 86 (RY-86) dyes showed degradation efficiency of 97.3, 78.57, 88.88, and 83.33 after 320 �min. ZnONPs exhibited remarkable antibacterial effectiveness against bacterial and fungal pathogens using the Minimum inhibitory concentration approach. Their MIC values were calculated, and free radical scavenging experiments showed antioxidant activity. The SH-ZnONPs were validated using HepG2 (IC50) cancerous cells lines and showed promising anti-cancer activity. These results revealed that SH-ZnO NPs had promising benefits that could be utilized as a viable therapeutic candidate. © 2023 The Author(s)

Item Type:	Journal Article
Publication:	Kuwait Journal of Science
Publisher:	Elsevier B.V.
Additional Information:	The copyright for this article belongs to author
Department/Centre:	Division of Mechanical Sciences > Materials Engineering (formerly Metallurgy)
Date Deposited:	04 Mar 2024 09:30
Last Modified:	04 Mar 2024 09:30
URI:	https://eprints.iisc.ac.in/id/eprint/84323

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