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A Multifaceted Scaffold for Building Bioactive Compounds: Phenothiazine

Upadhyay, PK and Pathak, S and Mishra, R and Kumar, R and Jain, A (2023) A Multifaceted Scaffold for Building Bioactive Compounds: Phenothiazine. In: Letters in Organic Chemistry, 20 (7). pp. 618-631.

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Official URL: https://doi.org/10.2174/1570178620666221202100529

Abstract

In the growing field of heterocyclic compounds, phenothiazine and the associated nucleus are among the most significant potential scaffolds with excellent pharmacological activities. The knowledge of chemistry, synthetic routes, and various physicochemical parameters of these compounds draws particular attention to create a chemical library. Related compounds synthesized by various routes have diverse pharmacological functions. The exhaustive search of phenothiazine literature helps the medicinal chemists who develop the molecules for designing new drugs. A broad view of the synthetic routes has been outlined in this study. This paper includes the chemistry, physiochemical properties, and various biological activities of phenothiazine and related compounds.

Item Type: Journal Article
Publication: Letters in Organic Chemistry
Publisher: Bentham Science Publishers
Additional Information: The copyright for this article belongs to the Bentham Science Publishers.
Keywords: biological activity; chemical library; heterocyclic moieties; Phenothiazine; synthesis; therapeutic
Department/Centre: Division of Mechanical Sciences > Materials Engineering (formerly Metallurgy)
Date Deposited: 31 Jul 2023 11:31
Last Modified: 31 Jul 2023 11:31
URI: https://eprints.iisc.ac.in/id/eprint/82759

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