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Reinforcing Synthetic Data for Meticulous Survival Prediction of Patients Suffering from Left Ventricular Systolic Dysfunction

Khan, MF and Gazara, RK and Nofal, MM and Chakrabarty, S and Dannoun, EMA and Al-Hmouz, R and Mursaleen, M (2021) Reinforcing Synthetic Data for Meticulous Survival Prediction of Patients Suffering from Left Ventricular Systolic Dysfunction. In: IEEE Access, 9 . pp. 72661-72669.

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Official URL: https://doi.org/10.1109/ACCESS.2021.3080617

Abstract

Congestive heart failure is among leading genesis of concern that requires an immediate medical attention. Among various cardiac disorders, left ventricular systolic dysfunction is one of the well known cardiovascular disease which causes sudden congestive heart failure. The irregular functioning of a heart can be diagnosed through some of the clinical attributes, such as ejection fraction, serum creatinine etcetera. However, due to availability of a limited data related to the death events of patients suffering from left ventricular systolic dysfunction, a critical level of thresholds of clinical attributes cannot be estimated with higher precision. Hence, this paper proposes a novel pseudo reinforcement learning algorithm which overcomes a problem of majority class skewness in a limited dataset by appending a synthetic dataset across minority data space. The proposed pseudo agent in the algorithm continuously senses the state of the dataset (pseudo environment) and takes an appropriate action to populate the dataset resulting into higher reward. In addition, the paper also investigates the role of statistically significant clinical attributes such as age, ejection fraction, serum creatinine etc., which tends to efficiently predict the association of death events of the patients suffering from left ventricular systolic dysfunction.

Item Type: Journal Article
Publication: IEEE Access
Publisher: Institute of Electrical and Electronics Engineers Inc.
Additional Information: The copyright for this article belongs to the Authors.
Keywords: heart failure; k-nearest neighbours; Pseudo reinforcement learning; support vector machine; synthetic data
Department/Centre: Division of Electrical Sciences > Electrical Engineering
Division of Interdisciplinary Sciences > Interdisciplinary Centre for Energy Research
Division of Interdisciplinary Sciences > Interdisciplinary Mathematical Sciences
Date Deposited: 09 Jun 2023 09:00
Last Modified: 09 Jun 2023 09:00
URI: https://eprints.iisc.ac.in/id/eprint/81827

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