Evolution of bacterial transcription factors: how proteins take on new tasks, but do not always stop doing the old ones

Visweswariah, Sandhya S and Busby, Stephen JW (2015) Evolution of bacterial transcription factors: how proteins take on new tasks, but do not always stop doing the old ones. In: TRENDS IN MICROBIOLOGY, 23 (8). pp. 463-467.

PDF Tre_in_Mic_23-8_463_2015.pdf - Published Version Restricted to Registered users only Download (819kB) | Request a copy

Abstract

Many bacterial transcription factors do not behave as per the textbook operon model. We draw on whole genome work, as well as reported diversity across different bacteria, to argue that transcription factors may have evolved from nucleoid-associated proteins. This view would explain a large amount of recent data gleaned from high-throughput sequencing and bioinformatic analyses.

Item Type:	Journal Article
Publication:	TRENDS IN MICROBIOLOGY
Publisher:	ELSEVIER SCI LTD
Additional Information:	Copy right for this article belongs to the ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
Keywords:	transcription factors; nucleoid associated proteins; bacterial gene regulation
Department/Centre:	Division of Biological Sciences > Molecular Reproduction, Development & Genetics
Date Deposited:	24 Sep 2015 06:28
Last Modified:	24 Sep 2015 06:28
URI:	http://eprints.iisc.ac.in/id/eprint/52405

Actions (login required)

View Item