Visweswariah, Sandhya S and Busby, Stephen JW (2015) Evolution of bacterial transcription factors: how proteins take on new tasks, but do not always stop doing the old ones. In: TRENDS IN MICROBIOLOGY, 23 (8). pp. 463-467.
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Official URL: http://dx.doi.org/10.1016/j.tim.2015.04.009
Abstract
Many bacterial transcription factors do not behave as per the textbook operon model. We draw on whole genome work, as well as reported diversity across different bacteria, to argue that transcription factors may have evolved from nucleoid-associated proteins. This view would explain a large amount of recent data gleaned from high-throughput sequencing and bioinformatic analyses.
Item Type: | Journal Article |
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Publication: | TRENDS IN MICROBIOLOGY |
Publisher: | ELSEVIER SCI LTD |
Additional Information: | Copy right for this article belongs to the ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND |
Keywords: | transcription factors; nucleoid associated proteins; bacterial gene regulation |
Department/Centre: | Division of Biological Sciences > Molecular Reproduction, Development & Genetics |
Date Deposited: | 24 Sep 2015 06:28 |
Last Modified: | 24 Sep 2015 06:28 |
URI: | http://eprints.iisc.ac.in/id/eprint/52405 |
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