Biomechanical Properties of Human Ascending Thoracic Aortic Dissections

Babu, Anju R and Byju, Achu G and Gundiah, Namrata (2015) Biomechanical Properties of Human Ascending Thoracic Aortic Dissections. In: JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 137 (8).

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Abstract

Thoracic aortic dissections are associated with a significant risk of morbidity and mortality, and currently challenge our understanding of the biomechanical factors leading to their initiation and propagation. We quantified the biaxial mechanical properties of human type A dissections (n = 16) and modeled the stress-strain data using a microstructurally motivated form of strain energy function. Our results show significantly higher stiffness for dissected tissues as compared to control aorta without arterial disease. Higher stiffness of dissected tissues did not, however, correlate with greater aortic diameter measured prior to surgery nor were there any age dependent differences in the tissue properties.

Item Type:	Journal Article
Publication:	JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME
Publisher:	ASME
Additional Information:	Copy right for this article belongs to the ASME, TWO PARK AVE, NEW YORK, NY 10016-5990 USA
Department/Centre:	Division of Mechanical Sciences > Mechanical Engineering Division of Interdisciplinary Sciences > Centre for Nano Science and Engineering
Date Deposited:	11 Aug 2015 06:36
Last Modified:	11 Aug 2015 06:36
URI:	http://eprints.iisc.ac.in/id/eprint/52056

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