Kumar, Mothish S and Prasad, Kavirayani R (2014) Enantiospecific Formal Total Synthesis of Iriomoteolide 3a. In: CHEMISTRY-AN ASIAN JOURNAL, 9 (12). pp. 3431-3439.
![]() |
PDF
che_asi_jou_9-12_3431_2014.pdf - Published Version Restricted to Registered users only Download (324kB) | Request a copy |
Official URL: http://dx.doi.org/ 10.1002/asia.201402593
Abstract
A formal total synthesis of the marine macrolide iriomoteolide3a is described. Salient features of the synthesis include the elaboration of a -keto phosphonate derived from D-(-)-tartaric acid and the extension of a chiral butyrolactone derived from L-glutamic acid. Ring-closing metathesis is employed to construct the macrolactone core of the natural product.
Item Type: | Journal Article |
---|---|
Publication: | CHEMISTRY-AN ASIAN JOURNAL |
Publisher: | WILEY-V C H VERLAG GMBH |
Additional Information: | Copyright for this article belongs to the WILEY-V C H VERLAG GMBH, BOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANY |
Keywords: | iriomoteolide3a; lactones; macrocycles; natural products; total synthesis |
Department/Centre: | Division of Chemical Sciences > Organic Chemistry |
Date Deposited: | 12 Jan 2015 04:54 |
Last Modified: | 12 Jan 2015 04:54 |
URI: | http://eprints.iisc.ac.in/id/eprint/50561 |
Actions (login required)
![]() |
View Item |