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A Circular Dichroism Study of Valinomycin Barium Ion Complex

Devarajan, S and Easwaran, KRK (1981) A Circular Dichroism Study of Valinomycin Barium Ion Complex. In: Biopolymers, 20 (5). pp. 891-899.


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Complex formation of valinomycin with $Ba^{2+}$ ions was investigated by circular dichroism spectroscopy. The results indicated that $Ba^{2+}$ forms entirely different types of complexes when compared with $K^+$. The data with perchlorate salt showed evidence for the formation of less stable $V_2C$ (peptide sandwich), VC (1:1), and $VC_2$ (ion sandwich) complexes followed by a stable final complex upon gradual addition of salt (V stands for valinomycin and C for the cation). This final complex possibly has a flat structure with no internal hydrogen bonds, similar to that of valinomycin in highly polar solvents. The possible complexation mechanism and the role played by anions and isopropyl side chains are highlighted.

Item Type: Journal Article
Publication: Biopolymers
Publisher: John Wiley & Sons, Inc.
Additional Information: The copyright belongs to John Wiley & Sons, Inc.
Department/Centre: Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited: 08 Dec 2005
Last Modified: 19 Sep 2010 04:21
URI: http://eprints.iisc.ac.in/id/eprint/4277

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