A fluorescent probe study of the solubilisation of cholesterol by biie salt-phospholipid micelles

Ranajit, Paul and Balaram, P (1978) A fluorescent probe study of the solubilisation of cholesterol by biie salt-phospholipid micelles. In: Biochemical and Biophysical Research Communications, 81 (3). pp. 850-857.

PDF 1.pdf - Published Version Restricted to Registered users only Download (448kB) | Request a copy

Abstract

The fluorescent probe dansyl cadaverine has been shown to bind strongly to mixed bile salt-phospholipid micelles containing unsaturation in the fatty acyl chains. Incorporation of cholesterol into the mixed micelles reduces the number of molecules of bound dansyl cadaverine without altering the binding affinity. These results suggest a tighter packing of the hydrocarbon matrix of the micelles in the presence of cholesterol.

Item Type:	Journal Article
Publication:	Biochemical and Biophysical Research Communications
Publisher:	Elesevier Science
Additional Information:	Copyright of this article belongs to Elesevier Science.
Department/Centre:	Division of Biological Sciences > Biochemistry Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited:	27 Oct 2010 07:00
Last Modified:	27 Oct 2010 07:00
URI:	http://eprints.iisc.ac.in/id/eprint/33179

Actions (login required)

View Item