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Paramagnetic probes in membrane biophysics

Sankaram, MB and Easwaran, KRK (1985) Paramagnetic probes in membrane biophysics. In: Journal of Chemical Sciences, 95 (1-2). pp. 103-115.

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Official URL: http://www.springerlink.com/content/0378j881660426...


The use of paramagnetic probes in membrane research is reviewed. Electron paramagnetic resonance studies on model and biological membranes doped with covalent and non-covalent spin-labels have been discussed with special emphasis on the methodology and the type of information obtainable on several important phenomena like membrane fluidity, lipid flip-flop, lateral diffusion of lipids, lipid phase separation, lipid bilayer phase transitions, lipid-protein interactions and membrane permeability. Nuclear magnetic resonance spectroscopy has also been effectively used to study the conformations of cation mediators across membranes and to analyse in detail the transmembrane ionic motions at the mechanistic level.

Item Type: Journal Article
Publication: Journal of Chemical Sciences
Publisher: Springer Link
Additional Information: Copyright of this article belongs to Springer Link.
Keywords: Membranes - electron paramagnetic resonance - nuclear magnetic resonance - spinlabels - paramagnetic probes
Department/Centre: Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited: 02 Feb 2010 08:04
Last Modified: 02 Feb 2010 08:04
URI: http://eprints.iisc.ac.in/id/eprint/23040

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