Fibre diffraction of lithium DNA shows structural variability and deviation from a regular helical structure for the B-form

Dutta, Santanu and Parrack, Pradip K and Sasisekharan, V (1984) Fibre diffraction of lithium DNA shows structural variability and deviation from a regular helical structure for the B-form. In: FEBS Letters, 176 (1). pp. 110-114.

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Abstract

Recently, reports have appeared which show structural variations in B-DNA and indicate deviations from a uniform helical structure. We report for the first time that these indications are also present in the B-form fibre diffraction patterns for the lithium salt of natural DNA. We have used an improved method of controlling the salt concentration in the fibres. Our results are based on the appearance and disappearance of meridional reflections on different layer lines depending upon the salt.

Item Type:	Journal Article
Publication:	FEBS Letters
Publisher:	Elsevier Science
Additional Information:	Copyright for this article belongs to Elsevier Science.
Keywords:	Fiber diffraction;Lithium B-DNA;Non-ideal helix;Structural variation.
Department/Centre:	Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited:	21 Jul 2009 10:29
Last Modified:	19 Sep 2010 05:32
URI:	http://eprints.iisc.ac.in/id/eprint/20395

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