Srinivasan, Y and Ramprasad, MP and Surolia, A (1985) Chemical Modification Studies of Gelonin - Involvement of Arginine Residues in Biological-Activity. In: FEBS Letters, 192 (1). pp. 113-118.
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Abstract
Gelonin inhibits protein synthesis by inactivating the eukaryotic 60 S ribosomal subunit by an unknown mechanism. The protein was purified in high yield by a new method using Cibacron blue F3GA-Sepharose. Chemical modification studies reveal that arginine residues are essential for biological activity.
| Item Type: | Journal Article |
|---|---|
| Publication: | FEBS Letters |
| Publisher: | Elsevier Science |
| Additional Information: | The copyright of this article belongs to Elsevier Science |
| Keywords: | Ribosome inactivating protein; Protein synthesis; Toxin; Chemical modification |
| Department/Centre: | Division of Biological Sciences > Molecular Biophysics Unit |
| Date Deposited: | 29 May 2009 09:09 |
| Last Modified: | 19 Sep 2010 05:31 |
| URI: | http://eprints.iisc.ac.in/id/eprint/20150 |
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