Subunit assembly of plant lectins

Sinha, Sharmistha and Gupta, Garima and Vijayan, Mamannamana and Surolia, Avadhesha (2007) Subunit assembly of plant lectins. In: Current Opinion in Structural Biology, 17 (5). pp. 498-505.

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Abstract

Lectins are a structurally diverse group of carbohydrate recognizing proteins that are involved in various biological processes and exhibit substantial structural diversity. Interestingly, in spite of having varied carbohydrate-binding specificities, they show modest variation in their secondary and tertiary structure. However, very similar tertiary folds give rise to a range of quaternary structures by simply varying the mutual orientations of the subunits involved. The variety in the quaternary structure generates multivalency in sugar specificities among lectins along with the requisite surface topology to allow for unobstructed recognition events.

Item Type:	Journal Article
Publication:	Current Opinion in Structural Biology
Publisher:	Elsevier
Additional Information:	Copyright of this article belongs to Elsevier.
Department/Centre:	Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited:	04 Jun 2008
Last Modified:	19 Sep 2010 04:45
URI:	http://eprints.iisc.ac.in/id/eprint/14170

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