Rapid procedure for the resolution of racemic gossypol

Sampath, DS and Balaram, P (1986) Rapid procedure for the resolution of racemic gossypol. In: Journal of the Chemical Society, Chemical Communications (9). pp. 649-650.

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Abstract

Racemic gossypol [(±)-I] was resolved rapidly and efficiently by high-performance liq. chromatog. sepn. of the diastereoisomeric adducts of (±)-I with L-phenylalaninol on an achiral, reversed-phase, C18 column. The sepd. adducts were hydrolyzed by 2M HCl to give (+)- and (-)-I with 50-60% recovery.

Item Type:	Journal Article
Publication:	Journal of the Chemical Society, Chemical Communications
Publisher:	Royal Society of Chemistry
Additional Information:	Copyright belongs to Royal Society of Chemistry
Department/Centre:	Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited:	09 May 2008
Last Modified:	19 Sep 2010 04:44
URI:	http://eprints.iisc.ac.in/id/eprint/13916

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