Electrospray mass spectrometric characterization of hemoglobin Q (Hb Q-India) and a double mutant hemoglobin S/D in clinical samples

Mandal, Amit Kumar and Bisht, Shveta and Bhat, Vijay S and Krishnaswamy, Patnam Rajagopalan and Balaram, Padmanabhan (2008) Electrospray mass spectrometric characterization of hemoglobin Q (Hb Q-India) and a double mutant hemoglobin S/D in clinical samples. In: Clinical Biochemistry, 41 (1-2). pp. 75-81.

PDF Electrospray_mass_spectrometric_characterization_of_hemoglobin.pdf Restricted to Registered users only Download (1MB) | Request a copy

Abstract

The clinical analysis of hemoglobin by ion exchange chromatography can result in ambiguities in identification of the nature of the globin chain present in patient samples. LC/ESI-MS provides rapid and precise determination of globin chain masses.

Item Type:	Journal Article
Publication:	Clinical Biochemistry
Publisher:	Elsevier
Additional Information:	Copyright of this article belongs to Elsevier.
Department/Centre:	Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited:	19 Feb 2008
Last Modified:	19 Sep 2010 04:42
URI:	http://eprints.iisc.ac.in/id/eprint/13054

Actions (login required)

View Item