The nomenclature and conformational analysis of lipids and lipid analogs

Chandrasekhar, Indira and Sasisekharan, V (1989) The nomenclature and conformational analysis of lipids and lipid analogs. In: Molecular and Cellular Biochemistry, 91 (1-2). pp. 173-182.

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Abstract

Lipids form an essential part of the biomembrane and it is of paramount importance to study their conformational aspects. It is found that the present methods of nomenclature for lipids are totally inadequate for describing these diverse amphipathic molecules. Further the existing methods are incompatible in terms of assignment of the absolute configuration. A systematic method for the naming of lipids which is rationally extendible to a wide class of amphipaths is described. The conformational features of the natural glycerolipids as well as a synthetic amphipath containing a glutamic acid moiety known to undergo interesting phase transitions, have been examined in detail using the framework of the current nomenclature system. The implications of the conformational flexibility of these molecules on assemblies of these systems is touched upon.

Item Type:	Journal Article
Publication:	Molecular and Cellular Biochemistry
Publisher:	Springer Netherlands
Additional Information:	Copyright of this article belongs to Springer Netherlands.
Keywords:	cell membrane;membrane lipids;amphipathic molecules
Department/Centre:	Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited:	03 Jan 2008
Last Modified:	19 Sep 2010 04:41
URI:	http://eprints.iisc.ac.in/id/eprint/12743

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