Biswakarma, D and Dey, N and Bhattacharya, S (2022) Molecular design of amphiphiles for Microenvironment-Sensitive kinetically controlled gelation and their utility in probing alcohol contents. In: Journal of Colloid and Interface Science, 615 . pp. 335-345.
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Abstract
Pyrene-laced �fluorescent� amphiphiles have been designed with a C4-alkyl chain as �hydrophobic spacer� and sugar moiety as hydrophilic residue. The amphiphile containing acetylacetohydrazide as a bridging unit (1) showed gel formation both in water and ethanol medium, while no gelation was observed with compound (2) with acetohydrazide as bridging unit. Accordingly, the self-assembly behavior of 1 was thoroughly investigated both in water and EtOH medium (as well as in their mixtures) in addition to their physicochemical properties. Though the gel formation kinetics was slower in water medium, the hydrogel showed superior mechanical strength (and thixotropic behavior) and improved thermal stability compared to the ethanolic gel. In water, the percolating H-bonding network with high cohesive force restricts the dynamics of the probe molecules, leading to some extent limited intermolecular interactions. However, hydrophobic interactions in water medium can result in the formation of rather �compact� nano-assembly (H-type aggregation) with prominent �-� stacking interactions. Such unique solvent-dependency of 1 was further utilized to screen commercially available beverages in terms of their alcohol contents and probe adulteration in beverages. Besides, the hydrogel also showed excellent stimuli responsiveness, a gel-to-sol transition, accompanied by fluorescence color change, was observed in the presence of insulin. © 2021 Elsevier Inc.
Item Type: | Journal Article |
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Publication: | Journal of Colloid and Interface Science |
Publisher: | Academic Press Inc. |
Additional Information: | The copyright for this article belongs to Academic Press Inc. |
Keywords: | Amphiphiles; Beverages; Ethanol; Fluorescence; Gels; Hydrogels; Hydrophobicity; Kinetics; Physicochemical properties; Probes; Sols, Adulteration in beverage; Alcohol contents; Bridging units; Gel formation; Gelation kinetics; Microenvironment-sensitivity; Microenvironments; Molecular design; Thixotropic behaviour; Water media, Gelation |
Department/Centre: | Division of Chemical Sciences > Organic Chemistry |
Date Deposited: | 21 Feb 2022 12:04 |
Last Modified: | 21 Feb 2022 12:04 |
URI: | http://eprints.iisc.ac.in/id/eprint/71395 |
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