Autosomal Clonal Monoallelic Expression: Natural or Artifactual?

RV, P and Sundaresh, A and Karunyaa, M and Arun, A and Gayen, S (2020) Autosomal Clonal Monoallelic Expression: Natural or Artifactual? In: Trends in Genetics . (In Press)

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Abstract

The prevalence of mitotically heritable clonal random monoallelic expression of autosomal genes (aRME) remains controversial. Specifically, presence of clonal aRME is well supported in vitro but remains elusive in vivo. Here, we provide critical insights into this matter and discuss whether prevalent clonal aRME is natural or artifactual. © 2020 Elsevier Ltd

Item Type:	Journal Article
Publication:	Trends in Genetics
Publisher:	Elsevier Ltd
Additional Information:	Copyright to this article belongs to Elsevier Ltd
Keywords:	allele; epigenetics; short survey; single cell RNA seq
Department/Centre:	Division of Biological Sciences > Molecular Reproduction, Development & Genetics
Date Deposited:	07 Jan 2021 11:44
Last Modified:	07 Jan 2021 11:44
URI:	http://eprints.iisc.ac.in/id/eprint/67228

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