Binita Chanu, S and Raza, MK and Musib, D and Pal, M and Pal, M and Roy, M (2020) Potent Photochemotherapeutic Activity of Iron(III) Complexes on Visible Light-induced Ligand to Metal Charge Transfer. In: Chemistry Letters, 49 (6). pp. 724-727.
Full text not available from this repository.Abstract
Five new ternary iron(III) complexes with phenolate-based ligands of general molecular formula, Fe(L1)B and Fe(L2)B, where L1 = 2-(bis(2-hydroxybenzyl)amino)acetic acid, L2 = 2-bis3,5-di(tert-butyl)-2-hydroxybenzylaminoacetic acid, B = phen (1,10-phenanthroline), ip (1H-imidazo4,5-f 1,10phen-anthroline) and pyip (2-(pyren-1-yl)-1H-imidazo4,5-f 1,10-phenanthroline) were synthesized and probed for visible light-induced cytotoxicity in human cervical carcinoma (HeLa) cells. The complexes in generating hydroxyl radicals from molecular oxygen on visible light-induced phenolate(O)¼Fe(III) or carboxylate(O)¼Fe(III) charge transfer prompted apoptosis in HeLa cells with IC50 values in the range of 4.624.3 ¯M while remaining non-toxic in dark. © 2020 The Chemical Society of Japan
| Item Type: | Journal Article |
|---|---|
| Publication: | Chemistry Letters |
| Additional Information: | cited By 0 |
| Department/Centre: | Division of Chemical Sciences > Inorganic & Physical Chemistry |
| Date Deposited: | 22 Sep 2021 10:02 |
| Last Modified: | 22 Sep 2021 10:02 |
| URI: | http://eprints.iisc.ac.in/id/eprint/65980 |
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