Hanchate, Vinayak and Kumar, Anil and Prabhu, Kandikere Ramaiah (2019) Synthesis of Naphthols by Rh(III)-Catalyzed Domino C-H Activation, Annulation, and Lactonization Using Sulfoxonium Ylide as a Traceless Directing Group. In: ORGANIC LETTERS, 21 (20). pp. 8424-8428.
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Abstract
Sulfoxonium ylide directed C-H activation catalyzed by the Rh(III)-catalyst has been disclosed. In this study, sulfoxonium ylide functions as a traceless directing group, which reacts with an unsymmetrical alkyne, 4-hydroxy-2-alkynoate, to form the corresponding furanone-fused 1-naphthols. The application of the methodology has been illustrated by synthesizing bromo lactones, which are used as an intermediate in synthesizing photochromic dichroic materials. We have also demonstrated the synthesis of an analogue of fimbricalyx lactone A.
Item Type: | Journal Article |
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Publication: | ORGANIC LETTERS |
Publisher: | AMER CHEMICAL SOC |
Additional Information: | Copyright of this article belongs to AMER CHEMICAL SOC |
Keywords: | CONSTITUENTS; PRESSURE; GOSSYPOL; ALKENES |
Department/Centre: | Division of Chemical Sciences > Organic Chemistry |
Date Deposited: | 13 Dec 2019 10:40 |
Last Modified: | 13 Dec 2019 10:40 |
URI: | http://eprints.iisc.ac.in/id/eprint/63894 |
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