FPGA-Based Lock-In Amplifier for Measuring the Electrical Properties of Individual Cells

Divakar, Dipin and Mahesh, Karthik and Varma, Manoj M and Sen, Prosenjit (2018) FPGA-Based Lock-In Amplifier for Measuring the Electrical Properties of Individual Cells. In: Proceedings of the 13th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, 22-26 April, 2018, Singapore, pp. 413-416.

PDF Proc_13th Ann_IEEE_Int_Conf_Apr22-26_2018_Singapore (2).pdf - Published Version Restricted to Registered users only Download (1MB) | Request a copy

Abstract

We report the design and validation of a low-cost and portable FPGA-based lock-in amplifier (LIA) for measuring the dielectric properties of cells through electrical impedance spectroscopy (EIS). The proposed design uses the phase sensitive measurement principle which detects the signal at a particular reference frequency and rejects the rest. By closely integrating the LIA with a custom-built instrumentation amplifier and a microfluidic device, we demonstrate the excellent ability of the system to suppress noise and detect impedance changes due to flowing red blood cells (RBCs).

Item Type:	Conference Proceedings
Series.:	International Conference on Nano-Micro Engineered and Molecular Systems NEMS
Publisher:	IEEE
Additional Information:	13th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems (IEEE-NEMS), Singapore, SINGAPORE, APR 22-26, 2018
Department/Centre:	Division of Interdisciplinary Sciences > Centre for Nano Science and Engineering
Date Deposited:	05 Jul 2019 06:21
Last Modified:	05 Jul 2019 06:21
URI:	http://eprints.iisc.ac.in/id/eprint/62819

Actions (login required)

View Item