Ramkumar, Rajagopal and Chandrasekaran, Srinivasan (2019) Catalyst-Free, Metal-Free, and Chemoselective Transamidation of Activated Secondary Amides. In: SYNTHESIS-STUTTGART, 51 (4). pp. 921-932.
![]() |
PDF
Syn_Stu_51-4_921-932_2019.pdf - Published Version Restricted to Registered users only Download (215kB) | Request a copy |
Abstract
A simple protocol, which is catalyst-free, metal-free, and chemoselective, for transamidation of activated secondary amides in ethanol as solvent under mild conditions is reported. A wide range of amines, amino acids, amino alcohols, and the substituents, which are problematic in catalyzed transamidation, are tolerated in this methodology. The transamidation reaction was successfully extended to water as the medium as well. The present methodology appears to be better than the other catalyzed transamidations reported recently.
Item Type: | Journal Article |
---|---|
Publication: | SYNTHESIS-STUTTGART |
Publisher: | GEORG THIEME VERLAG KG |
Additional Information: | Copyright for this article belongs to Georg Thieme Verlag KG. |
Keywords: | amino acid; catalyst-free; metal-free; chemoselective; secondary amide; transamidation |
Department/Centre: | Division of Chemical Sciences > Organic Chemistry |
Date Deposited: | 11 Mar 2019 10:29 |
Last Modified: | 11 Mar 2019 10:29 |
URI: | http://eprints.iisc.ac.in/id/eprint/61949 |
Actions (login required)
![]() |
View Item |