Patra, Atanu and James, Anjima and Das, Tamal Kanti and Biju, Akkattu T (2018) Oxidative NHC Catalysis for the Generation of Imidoyl Azoliums: Synthesis of Benzoxazoles. In: JOURNAL OF ORGANIC CHEMISTRY, 83 (23). pp. 14820-14826.
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Abstract
N-Fleterocyclic carbene (NHC)-catalyzed intramolecular cyclization of aldimines generated from 2-amino phenols and aromatic aldehydes leading to the synthesis of 2-arylbenzoxazoles under mild conditions is presented. The reaction proceeds via the generation of the aza-Breslow intermediates from imines and NHC, which under oxidative conditions form the key imidoyl azoliums and a subsequent intramolecular cyclization furnishes the product. The reaction tolerates a broad range of functional groups, and the products are formed in generally good yields.
Item Type: | Journal Article |
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Publication: | JOURNAL OF ORGANIC CHEMISTRY |
Publisher: | AMER CHEMICAL SOC |
Additional Information: | Copyright of this article belongs to AMER CHEMICAL SOC |
Department/Centre: | Division of Chemical Sciences > Organic Chemistry |
Date Deposited: | 10 Feb 2019 09:38 |
Last Modified: | 10 Feb 2019 09:38 |
URI: | http://eprints.iisc.ac.in/id/eprint/61358 |
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