Two-dimensional nuclear Overhauser effect experiment in a protein: the first NOESY (1979-80)

Kumar, Anil (2003) Two-dimensional nuclear Overhauser effect experiment in a protein: the first NOESY (1979-80). In: Magnetic Resonance in Chemistry, 41 (S1). S26-S32.

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Abstract

The development of two-dimensional proton-proton nuclear Overhauser effect spectroscopy was a seminal development in the algorithm of protein structure determination by liquid-state NMR. This article provides a historical and personal view of the various facilities, challenges and solutions in the successful development of this experiment for biomolecules in Professor Wuthrich's laboratory during the academic year 1979-80.

Item Type:	Journal Article
Publication:	Magnetic Resonance in Chemistry
Publisher:	John Wiley & Sons, Ltd.
Additional Information:	The copyright belongs to John Wiley & Sons, Ltd.
Keywords:	two dimensional nmr;noesy;cosy;proton proton noe;proteins; biomolecules;secondary structure;three dimensional structure; liquid state nmr
Department/Centre:	Division of Chemical Sciences > Sophisticated Instruments Facility (Continued as NMR Research Centre) Division of Physical & Mathematical Sciences > Physics
Date Deposited:	28 Feb 2006
Last Modified:	19 Sep 2010 04:23
URI:	http://eprints.iisc.ac.in/id/eprint/5589

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