Prasad, Puja and Khan, Imran and Sasmal, Pijus K and Koley, Debasis and Kondaiah, Paturu and Chakravarty, Akhil R (2011) Planar triazinium cations from VO2+-assisted ring cyclizations: a remarkably efficient thiazole species for nuclear staining, PDT and anaerobic photocleavage of DNA. In: Chemical Communications, 47 (13). pp. 3954-3956.
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Abstract
Planar triazinium cationic species, from VO2+-assisted cyclization of 1-(2-thiazolylazo)-2-naphthol, shows efficient DNA intercalative binding, visible light-induced anaerobic plasmid DNA photocleavage activity and photocytotoxicity in HeLa and MCF-7 cancer cells by an apoptotic pathway with selective localization of the compound in the nucleus as evidenced from the nuclear staining and confocal imaging.
Item Type: | Journal Article |
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Publication: | Chemical Communications |
Publisher: | Royal Society of Chemistry |
Additional Information: | Copyright of this article belongs to Royal Society of Chemistry. |
Department/Centre: | Division of Biological Sciences > Molecular Reproduction, Development & Genetics Division of Chemical Sciences > Inorganic & Physical Chemistry |
Date Deposited: | 06 Apr 2011 09:24 |
Last Modified: | 06 Apr 2011 09:24 |
URI: | http://eprints.iisc.ac.in/id/eprint/36611 |
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