Effect of 2-allyl-2-isopropylacetamide on poly(adenylic acid)-containing ribonucleic acid.

Sardana, MK and Padmanaban, G (1976) Effect of 2-allyl-2-isopropylacetamide on poly(adenylic acid)-containing ribonucleic acid. In: Biochemical Journal, 158 (2). pp. 169-174.

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Abstract

A single administration of 2-allyl-2-isopropylacetamide, a porphyrinogenic drug, enhanced the 32P-labelling of nucleoplasmic as well as cytoplasmic poly(A)-containing RNA in rat liver. The synthesis of total microsomal RNA is only marginally increased under these conditions. The drug enhances the labelling of a variety of cytoplasmic poly(A)-containing RNA species, and this effect is counteracted by the simultaneous administration of haemin. 2-Allyl-2-isopropylacetamide also enhanced the release of RNA from the nucleus to the cytoplasm.

Item Type:	Journal Article
Publication:	Biochemical Journal
Publisher:	The Biochemical Society
Additional Information:	Copyright of this article belongs to the Biochemical Society.
Department/Centre:	Division of Biological Sciences > Biochemistry
Date Deposited:	09 Dec 2009 11:40
Last Modified:	19 Sep 2010 05:49
URI:	http://eprints.iisc.ac.in/id/eprint/24277

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