Icosahedral DNA Nanocapsules by Modular Assembly

Bhatia, Dhiraj and Mehtab, Shabana and Krishnan, Ramya and Indi, Shantinath S and Basu, Atanu and Krishnan, Yamuna (2009) Icosahedral DNA Nanocapsules by Modular Assembly. In: Angewandte Chemie-International Edition, 48 (23). pp. 4134-4137.

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Abstract

The construction of well-defined 3D architectures is one of the greatest challenges of self-assembly. Nanofabrication through molecular self-assembly has resulted in the formation of DNA polyhedra with the connectivities of cubes,[1] tetrahedra,[2,3] octahedra,[4, 5] dodecahedra,[3] and buckminsterfullerene.[ 3] DNA polyhedra could also function as nanocapsules and thereby enable the targeted delivery of entities encapsulated from solution. Key to realizing this envisaged function is the construction of complex polyhedra that maximize encapsulation volumes while preserving small. pore size.

Item Type:	Journal Article
Publication:	Angewandte Chemie-International Edition
Publisher:	John Wiley and Sons
Additional Information:	Copyright of this article belongs to John Wiley and Sons.
Keywords:	DNA;five-way junctions;nanotechnology;platonic solids; self-assembly.
Department/Centre:	Division of Biological Sciences > Microbiology & Cell Biology
Date Deposited:	12 Aug 2009 10:53
Last Modified:	19 Sep 2010 05:35
URI:	http://eprints.iisc.ac.in/id/eprint/21011

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