Expression of progesterone receptor mRNA in the first trimester human placenta

Shanker, YG and Sharma, SC and Rao, AJ (1997) Expression of progesterone receptor mRNA in the first trimester human placenta. In: Biochemistry And Molecular Biology International, 42 (6). pp. 1235-1240.

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Abstract

The human placenta produces large quantities of progesterone, the function and target tissues of action of which during pregnancy are not completely understood. Although it has been suggested that placenta itself could be a potential target tissue for progesterone action, there is no conclusive evidence for the presence of progesterone receptors in the human placenta. We provide evidence for the expression of progesterone receptor mRNA in the human placenta by reverse transcription coupled to polymerase chain reaction (RT-PCR). This was further confirmed by Southern hybridization, restriction analysis and sequencing of the PCR amplified fragment.

Item Type:	Journal Article
Publication:	Biochemistry And Molecular Biology International
Publisher:	John Wiley and Sons
Additional Information:	Copyright of this article belongs to John Wiley and Sons.
Keywords:	Progesterone receptor;human placenta;progesterone;RT-PCR.
Department/Centre:	Division of Biological Sciences > Biochemistry
Date Deposited:	19 Jul 2009 06:35
Last Modified:	19 Sep 2010 05:26
URI:	http://eprints.iisc.ac.in/id/eprint/18967

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