Madyastha, KM and Venkatakrishnan, K (1999) Biocatalyst-mediated expansion of ring D in azadirachtin, a potent insect antifeedant from Azadirachta indica. In: Tetrahedron Letters, 40 (28). pp. 5243-5246.
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Abstract
A microorganism identified as Nocardia Sp.capable of converting azadirachtin 1 into three metabolites, viz. 3-deacetylazadirachtin 2, 1-detigloyl-3-deacetyl-azadirachtin-1-ene-3-one 3 and 1-detigloyl-3-deacetyl-11,19-deoxa-12,19-oxa-11-oxo-azadirachtin-1-ene-3-one 4, has been isolated. This is the first report on the functionalization of azadirachtin using biocatalysts wherein two novel, hitherto unknown metabolites have been isolated and characterized.
Item Type: | Journal Article |
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Publication: | Tetrahedron Letters |
Publisher: | Elsevier |
Additional Information: | Copyright of this article belongs to Elsevier. |
Keywords: | Azadirachta indica;Azadirachtin;Biocatalyst;Nocardia Sp.;α,β-unsaturated ketone;α-keto-δ-lactone |
Department/Centre: | Division of Chemical Sciences > Organic Chemistry |
Date Deposited: | 15 Oct 2007 |
Last Modified: | 19 Sep 2010 04:40 |
URI: | http://eprints.iisc.ac.in/id/eprint/12094 |
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