The first total synthesis of the novel triquinane natural products pleurotellol and pleurotellic acid

Mehta, Goverdhan and Murthy, Sai Krishna A (2003) The first total synthesis of the novel triquinane natural products pleurotellol and pleurotellic acid. In: Tetrahedron Letters, 44 (28). pp. 5243-5246.

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Abstract

The first total synthesis of the triquinane based sesquiterpenoid antibiotics (±)-pleurotellol and (±)-pleurotellic acid isolated from the fermentation broth of Pleurotellus hypnophilus have been accomplished. The triquinane based bis-enone system obtained via photo-thermal metathesis in a caged pentacyclic dione has been elaborated to the natural products through carefully crafted functional group transformations.

Item Type:	Journal Article
Publication:	Tetrahedron Letters
Publisher:	Elsevier Science
Additional Information:	Copyright for this article belongs to Elsevier Science.
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	08 Jul 2004
Last Modified:	19 Sep 2010 04:13
URI:	http://eprints.iisc.ac.in/id/eprint/1000

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