Selvaraj, J and Rajendran, V and Ramalingam, B (2021) Nanovaccine: A Modern Approach to Vaccinology. [Book Chapter]
Full text not available from this repository.Abstract
Currently, available established vaccines generally consisted of live, killed, attenuated, or inactivated microbial often generate many unwanted side effects. For the enhancements of current vaccines, further developments required due to weak immunogenicity, instability, toxicity, and multiple administrations; to conquer this restriction, the platform of nanotechnology has a newer expectation of being integrated towards the development of a vaccine. Nanoscale technologies are in medicine evoked more than four decades age. i.e., Liposome (Phospholipids bilayer based nanoparticles) have been used in the pharmaceutical industry since 1960. Nanovaccinology has achievable to push the horizon of modern vaccine discovery. The Nanovaccine provides a chance to strengthen the cellular and humoral immune responses. Modification of nanocarrier surfaces with a variety of targeting part consent the delivery of antigens to precise cell surface receptors, through stimulating specific and selective immune responses. The ability of the nanoparticle-based vaccine not particularly to delivery of target, and likewise antigen upgraded stability and immunogenicity. Currently, more numbers of preventive nano-vaccine have approved for human use, and few more are in the trails of pre-clinical and clinical phases and existing available nano-vaccine induce humoral and cell-mediated immunity. © 2021, Springer Nature Switzerland AG.
| Item Type: | Book Chapter |
|---|---|
| Publication: | Nanotechnology in the Life Sciences |
| Series.: | Nanotechnology in the Life Sciences |
| Publisher: | Springer Science and Business Media B.V. |
| Additional Information: | The copyright for this article belongs to Springer Science and Business Media B.V. |
| Department/Centre: | Division of Biological Sciences > Molecular Biophysics Unit |
| Date Deposited: | 22 Mar 2021 11:54 |
| Last Modified: | 22 Mar 2021 11:54 |
| URI: | http://eprints.iisc.ac.in/id/eprint/68555 |
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