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Thermodynamic characterization of oligo dG. poly rC hybrid helixes

Thomas, Thresia and Nandi, US and Poddar, SK (1986) Thermodynamic characterization of oligo dG. poly rC hybrid helixes. In: Indian Journal of Biochemistry & Biophysics, 23 (4). pp. 192-196.

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The formation and thermal stability of oligo(dG) and poly(rC) hybrid helixes were studied by UV spectroscopy and melting temp. (Tm) measurements. The thermodynamic parameters (DH and DS) and the stability const. of hybrid helix formation were calculated. The hybrid helixes are less stable than the corresponding ribo analogs. This is significant from a biol. standpoint, since hybrid helixes are transiently formed and dissocd. during transcription.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to National Institute of Science Communication and Information Resources
Department/Centre: Division of Biological Sciences > Biochemistry
Depositing User: Dipti Chaurasia
Date Deposited: 28 Apr 2008
Last Modified: 27 Aug 2008 13:20
URI: http://eprints.iisc.ac.in/id/eprint/13783

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