Easwaran, KRK and Balasubramanian, SV (1990) Spectroscopic studies on the structure and aggregation of calcium ionophore, A23187. In: 5th Proceedings UNESCO International Conference, 1989.
Full text not available from this repository. (Request a copy)Abstract
Studies on the structure of calcium ionophore, A23187, using IR, UV, CD, fluorescence and NMR methods indicated that this ionophore forms a dimer in nonpolar solvents such as chloroform. When incorporated into a phospholipid vesicle, the spectra showed remarkable time dependent changes indicating further aggregation of the dimer into a stacked dimeric structure in dipalmitoylphosphatidylcholine vesicle. Results point to the possibility of A23187 transporting divalent cations across membranes by a pore rather than by a diffusive carrier model.
| Item Type: | Conference Proceedings |
|---|---|
| Publisher: | Birkhaeuser |
| Additional Information: | Copyright of this article belongs to Birkhaeuser. |
| Keywords: | Spectroscopic studies;calcium ionophore;fluorescence;NMR methods |
| Department/Centre: | Division of Biological Sciences > Molecular Biophysics Unit |
| Date Deposited: | 28 Dec 2007 |
| Last Modified: | 08 Feb 2012 07:24 |
| URI: | http://eprints.iisc.ac.in/id/eprint/12575 |
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