ePrints@IIScePrints@IISc Home | About | Browse | Latest Additions | Advanced Search | Contact | Help

Enantiospecific synthesis of (-)-muricatacin from L-(+)- tartaric acid

Prasad, Kavirayani R and Anbarasan, Pazhamalai (2006) Enantiospecific synthesis of (-)-muricatacin from L-(+)- tartaric acid. In: Tetrahedron: Asymmetry, 17 (17). pp. 2465-2467.

[img] PDF
Restricted to Registered users only

Download (113kB) | Request a copy


Enantiospecific synthesis of (-)-muricatacin, a bio-active lactone comprising of a 5-hydroxyalkylbutan-4-olide structural component has been achieved from L-(+)-tartaric acid. The key step involves a disteroselective reduction of a $C_2$-symmetric 1,4-diketone derived from tartaric acid followed by a selective Grignard reagent addition.

Item Type: Journal Article
Publication: Tetrahedron: Asymmetry
Publisher: Elsevier
Additional Information: Copyright of this article belongs to Elsevier.
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 30 Nov 2007
Last Modified: 19 Sep 2010 04:33
URI: http://eprints.iisc.ac.in/id/eprint/9116

Actions (login required)

View Item View Item