Birth of organocatalysis by N-heterocyclic carbenes

Chakraborty, S and Biju, AT (2024) Birth of organocatalysis by N-heterocyclic carbenes. In: Nature Catalysis, 7 (10). pp. 1060-1062.

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Abstract

Thiamine, a common enzymatic cofactor, catalyses the benzoin condensation. From 1943, a panoply of mechanistic proposals were invoked to explain the intriguing transformation until two seminal papers by Ronald Breslow about 15 years after the discovery of this reaction helped resolve the mechanistic conundrum and heralded the birth of NHC-organocatalysis. © Springer Nature Limited 2024.

Item Type:	Editorials/Short Communications
Publication:	Nature Catalysis
Publisher:	Nature Research
Additional Information:	The copyright for this article belongs to Nature Research
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	18 Nov 2024 17:02
Last Modified:	18 Nov 2024 17:02
URI:	http://eprints.iisc.ac.in/id/eprint/86828

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