Agharkar, AN and Hajra, D and Roy, D and Jaiswal, V and Kabi, P and Chakravortty, D and Basu, S (2024) Evaporation of bacteria-laden surrogate respiratory fluid droplets: On a hydrophilic substrate vs contact-free environment confers differential bacterial infectivity. In: Physics of Fluids, 36 (3).
|
PDF
phy_flu_36_3_2024.pdf - Published Version Download (6MB) | Preview |
Abstract
The transmission of viruses/bacteria causes infection predominantly via aerosols. The transmission mechanism of respiratory diseases is complex, which includes direct or indirect contact, large droplet, and airborne routes apart from close contact transmission. With this premise, two modes of droplet evaporation are investigated to understand its significance in airborne disease transmission; a droplet in a contact-free environment, which evaporates and forms droplet nuclei, and a droplet on a hydrophilic substrate (fomite). The study examines mass transport, the deposition pattern of bacteria in the precipitates, and their survival and virulence. The osmotic pressure increases with the salt concentration, inactivating the bacteria embedded in the precipitates with accelerated evaporation. Furthermore, the bacteria's degree of survival and enhanced pathogenicity are compared for both evaporation modes. The striking differences in pathogenicity are attributed to the evaporation rate, oxygen availability, and reactive oxygen species generation. © 2024 Author(s).
| Item Type: | Journal Article |
|---|---|
| Publication: | Physics of Fluids |
| Publisher: | American Institute of Physics |
| Additional Information: | The copyright for this article belongs to authors. |
| Keywords: | Drops; Evaporation; Hydrophilicity; Osmosis; Oxygen; Transmissions; Viruses, Airborne disease; Contact free; Deposition patterns; Direct contact; Disease transmission; Droplet evaporation; Fluid droplets; Hydrophilic substrate; Indirect contact; Transmission mechanisms, Bacteria |
| Department/Centre: | Division of Biological Sciences > Microbiology & Cell Biology Division of Interdisciplinary Sciences > Interdisciplinary Centre for Energy Research Division of Mechanical Sciences > Mechanical Engineering |
| Date Deposited: | 22 May 2024 04:23 |
| Last Modified: | 22 May 2024 04:23 |
| URI: | https://eprints.iisc.ac.in/id/eprint/84826 |
Actions (login required)
 |
View Item |
