Innovative and sustainable synthesis and structure of novel N-substituted hexahydroacridine derivatives

Vinoth, N and Kalaiarasi, C and Lalitha, A (2024) Innovative and sustainable synthesis and structure of novel N-substituted hexahydroacridine derivatives. In: Journal of Physical Organic Chemistry .

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Abstract

An efficient and green synthesis of tetramethyl-10-(phenylamino)-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione derivatives has been achieved from various substituted aryl aldehydes, 5,5-dimethyl-3-(2-phenylhydrazinyl)cyclohex-2-enone and dimedone in aqueous ethanol medium. Environment-friendly reaction, excellent yields, operational simplicity and shorter reaction times are the significant features of the present protocol. All the synthesized compounds were characterized by various spectroscopic techniques and X-ray crystal diffraction studies. © 2024 John Wiley & Sons Ltd.

Item Type:	Journal Article
Publication:	Journal of Physical Organic Chemistry
Publisher:	John Wiley and Sons Ltd
Additional Information:	The copyright for this article belongs to John Wiley and Sons Ltd.
Keywords:	Acridine; Aqueous ethanol; Aryl aldehydes; Catalyst-free; Efficient synthesis; Green synthesis; Greener solvents; N-heterocycles; Tetramethyl; X-ray crystallographic, X ray crystallography
Department/Centre:	Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited:	15 May 2024 10:28
Last Modified:	15 May 2024 10:28
URI:	https://eprints.iisc.ac.in/id/eprint/84478

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