Precise and Low Volume Sampling Using Microfluidic Device

Sharma, NK and Sen, P (2022) Precise and Low Volume Sampling Using Microfluidic Device. In: 2022 IEEE International Conference on Emerging Electronics, 11 -14 Dec 2022, Bangalore.

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Abstract

We report a microfluidic device platform to precisely sample low volumes of fluids such as blood for disease diagnosis. It comprises a custom-engineered T-channel, a microfabricated PDMS device. The sampling rate (Q2) is controlled by the design of the sampling channels and the withdrawal rate (Q1) of continuous flow using a syringe pump in the main channel. Three devices with a flow rate ratio (Q1/Q2) of 10, 50, and 100 were designed and tested. The minimum experimental Q2 was found to be 160 nl/min against Q1 of 1.7 μ1/min. The reported device has the capability to reduce the dead volumes, and precisely sample low volumes from regions where the sample volume is limited such as cerebrospinal fluid. © 2022 IEEE.

Item Type:	Conference Paper
Publication:	2022 IEEE International Conference on Emerging Electronics, ICEE 2022
Publisher:	Institute of Electrical and Electronics Engineers Inc.
Additional Information:	The copyright for this article belongs to
Keywords:	Low-volume sampling; Microfluidics; T-Channel
Department/Centre:	Division of Interdisciplinary Sciences > Centre for Nano Science and Engineering
Date Deposited:	28 Jun 2023 06:06
Last Modified:	28 Jun 2023 06:06
URI:	https://eprints.iisc.ac.in/id/eprint/82194

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